glutathione pathway oxidative stress pathway. The implications of MA exposure on oxidative Regulation of Ascorbate-Glutathione Pathway in

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[2] Weiss JB, Phillips CJ, Malin EW, Gorantla VS, Harding JW, Salgar SK

10.1016/S0076-6879(05)01015-3 Methods Enzymol

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In particular, our study showed that the intracellular depletion of GSH is able to induce cellular stress in NO-producing cells through a NO-dependent mechanism, such as inhibition of CcOX activity, DNA damage, and S-NO and 3-nitrotyrosine (NO 2 -Tyr) protein accumulation ( Figure 1 )

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