Since B12 is water-soluble, excess amounts are excreted through urine rather than stored in the body, reducing the risk of toxicity
Instead use 500mcg of inactive B12 (hydroxycobalamin) ONLY, without any other B vitamins to start
You can become deficient in vitamin B12 if you dont get enough of it over time
Concurrent Use with Other NNMT Inhibitors or Methylation Modulators Combining with supplements or drugs that also inhibit NNMT or alter methylation (e.g., SAMe , niacin , methylfolate , resveratrol ) could lead to: Excess NAD accumulation Methyl donor depletion Unpredictable metabolic effects Use caution and monitor methylation-related pathways if stacking 3
Not everyone needs injections, though
Every compound from BioLongevity Labs ships with a COA tied to its specific batch, so researchers can confirm exactly what they received before it enters a protocol