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Participants with hyperglycemia had higher odds of long-term retention (OR = 2.16, 95% CI: 1.32, 3.56) but were less likely to engage via messages (OR = 0.50, 95% CI: 0.31, 0.82) compared to those without hyperglycemia

Bibcode:2003PNAS..100.9785L

However, folate supplementation can mask these haematological changes whilst neurological damage continues, highlighting the importance of checking B12 status before commencing folate therapy

Some users report generalized body aches on tirzepatide or specific muscle pain

In addition, your muscles do not work as efficiently as they should, so they wear out faster