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Where serum B12 results are borderline or do not fit the clinical picture, further tests such as active B12 (holotranscobalamin), methylmalonic acid, or homocysteine may be helpful

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However, direct evidence showing faster workout or injury recovery in healthy individuals is limited, so their role in fitness and rehabilitation should be viewed as supportive rather than proven

Altogether this emphasises the need for further research to clarify the receptor-specific mechanisms of sCT and to explore potential species-specific differences in its interactions with AMYRs, particularly among rats, mice, and humans