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Cell Death Dis 12 , 206 (2021)

Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1

10.4331/wjbc.v6.i4.301 World J

While Adenosylcobalamin supports mitochondrial energy production, Methylcobalamins direct role in neurological function provides broader therapeutic benefits

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