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For example, a phase 2 RCT testing an inhibitor of 11-beta-hydroxysteroid dehydrogenase 1 (11-HSD1)an enzyme involved in the conversion of inert cortisone to active cortisol, which, when elevated in CSF, has been linked to cognitive declinefailed to find any cognitive benefit for AD patients with mild to moderate symptoms (Seckl, 2024)

The result is the debilitating cognitive dysfunction commonly referred to as "brain fog." Patients often describe this as wading through mental molasses, struggling with word retrieval, short-term memory loss, and a profound inability to concentrate

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GLP-1

A20 promotes liver regeneration by decreasing SOCS3 expression to enhance IL-6/STAT3 proliferative signals

At one capsule a day, 60 capsules would run closer to two months, not one