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Self-reported community cycling is a more conservative pattern than the trial supported, driven by community-level concerns about receptor downregulation and long-term tolerability that the 48-week trial window did not directly address

doi: 10.1002/(ISSN)1096-9861 183 RossCARuggieroDAJohTHParkDHReisDJ

This strategy effectively reduces the incidence of side effects, particularly gastrointestinal issues

2024;47(Suppl 1):S52-S76

Traditional weight loss methods, including diet and exercise, though effective, often require significant time and dedication, which many find challenging

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