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A 20% nausea spike is expected during weeks 1-2 of the transition due to the overlap of both medications effects

With a half-life of approximately six days, missing one dose reduces but does not eliminate blood levels

It adds that if short-term use is the intent from the start, a provider should design a gradual tapering strategy and a post-discontinuation follow-up protocol rather than leaving the ending unplanned

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The use of nano-emulsified capsaicin yielded similar results to non-emulsified capsaicin, with the added benefit of no negative impacts on the stomach

Dosage: See package insert