Use in pediatric or neonatal populations should follow institutional guidelines and medical supervision
While GHK-Cu is generally well-tolerated in topical research, certain contraindications or precautions should be considered, especially for systemic research or in specific populations: Systemic Research: For systemic applications, GHK-Cu is generally not recommended for subjects who are pregnant, breastfeeding, have active cancer, or suffer from Wilsons disease (a condition involving copper accumulation)
Long-term studies have shown particularly interesting results
Schwartz AR, Patil SP, Squier S, Schneider H, Kirkness JP, Smith PL
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222 This variability depends on NAPRT expression level of the original tissue