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After sedated with Avertin (240 mg/kg), mice were preconditioned by chest hair removal and placed in a supine position on an animal handling platform

To investigate whether the photothermal effect of a high light intensity of 0.5 W/cm 2 affects the oxygen production capacity of GHEA in GHEA@Gel, GHEA@Gel samples containing GHEA cells at different concentrations were placed under 658 nm laser irradiation for 5 min

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During the study, we observed varying degrees of weight loss in IMQ-treated mice, with the IMQ-induced group showing continuous weight decline

This is very important because: It is an oral GLP-1 medicine (no injection needed) Patients taking the highest dose lost about 12.4% of body weight It is easy to take (no need to take it on an empty stomach) This approval brings strong competition to Novo Nordisk and its oral Wegovy pill

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