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GLP-1 receptor agonists take center stage, tickling the brain's appetite regulation center in the hypothalamus and leaving it giggling with delight

Biochem Biophys Res Commun (2018) 506(4):97682

It potentially can cause pancreatitis

Since GLP-1 medications mimic the action of a peptide produced in the GI tract, most reported mild side effects are associated with the digestive tract

These studies suggest that GLP-1 may mediate cholesterol outflow in hepatocytes through the LXR-ABCA1 pathway, consequently avoiding large amounts of cholesterol accumulation in cells

My experience shows that in some patients, complete discontinuation of the dopaminergic medication may not always be possible. Devnani adds that opioids may be used carefully during the weaning process to manage any breakthrough symptoms