Additionally, recent studies indicate that GLP-1 RA can benefit individuals living with type 1 and 2 diabetes [61]
Pregnancy and Breastfeeding: Most GLP-1 weight loss studies do not allow participation from pregnant or breastfeeding women due to unknown risks to the baby and potential hormonal effects
Of the 53 100 eligible for inclusion, 2003 were identified as GLP1 RA initiators, and 51 097 were identified as metformin users
4,6 A key issue in the physiology of type 2 diabetes (T2DM) is the reduced incretin effect, which mainly results from decreased activity of the primary incretin hormones, GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic peptide)
Future research should concentrate on discovering optimum microbiome biomarkers for therapy selection and creating microbiome-targeted adjuvant medicines
Companies market them as supplements, but they do not have the clinical testing needed to get medical approval or be used as prescriptions