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Wu T, Rayner CK, Jones K, and Horowitz M

Sobo evaluates weight through a medical lens, looking at appetite regulation, insulin resistance, thyroid function, hormones, sleep, stress, inflammation, nutrient status, body composition, prior diet history, medication use, and long-term maintenance needs

Weeks 9-12: 8 mg per week (160 units, requires 2 draws from 1 mL syringe or a larger syringe) The 8 mg dose is where retatrutide separates from the competition

The occurrence and magnitude of WR after MBS differs in the literature according to the type of surgery, definition of WR, length of the follow-up period, and follow-up rates

This is a tolerability dose, not a treatment dose for weight loss or HbA1c

Healthcare professionals worried about over-prescription or long-term unknowns raise valid cautions