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doi: 10.1136/ard.2010.131235 40 GossageDLCieslarovBApSZhengHXinYLalPet al

Pickart's work and subsequent studies document collagen synthesis upregulation, fibroblast proliferation stimulation, and re-epithelialization support in wound models mechanisms consistent with standard wound-healing research endpoints [9,10]

4 Research on berberine shows modest effects

In addition, a small pilot safety study published in Alternative Therapies in Health and Medicine showed that intravenous infusions of BPC-157 up to 20 milligrams were well-tolerated with no reported adverse effects in healthy adults, providing initial evidence that the peptide can be administered safely, a necessary step before larger efficacy trials on healing outcomes are conducted

However, some patients experience unexpected weight gain or fail to lose weight whilst taking this medication

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