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Neurotoxicol Teratol 32:391397 Rajesh V, Deepan N, Anitha V, Kalaiselvan D, Jayaseelan S, Sivakumar P, Ganesan V (2020) Heart malformation is an early response to valproic acid in developing zebrafish

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In the case of Apert syndrome, for example, there is good reason to believe that the causative mutation (in this case, predominantly a 755C-G transversion in the FGFR-2 gene) arises in spermatogonia and is selectively retained in the germinal epithelium because the mutant germ cells enjoy an unspecified selective advantage [4]

These studies highlight the potential of GLS inhibitors in cancer therapy, providing insights into the modulation of the immune microenvironment and the development of innovative treatment strategies