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Similarly, pyroptosis, a caspase-1-dependent form of cell death, induces gasdermin-D pore formation in the plasma membrane, culminating in cellular swelling and rupture [87, 88]

5.3 Glutathione and ASD Glutathione is another important molecule, which ratio between the reduced form (GSH) and the oxidized one (GSSG) dictate and influences the redox status of the cell

In many other forms of arthritis, only the joints are affected

Overcoming the drug resistance of MET-TKIs and ICIs, as well as their toxic and side effects that may affect the drug efficacy, remains a critical challenge

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