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In particular, evidence has been provided that active Nrf2 inhibits the transcription of angiotensin converting enzyme 2 (ACE2) which, interacting with the spike protein of the virus capsid, represents the site for virus entry [148]

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a class of medications that mimic the action of the natural hormone GLP-1

This pattern is similar to other GLP-1based medications, where increasing the dose can improve results but also raises the chance of side effects

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GLP-1 RAs are a class of pharmacological agents that mimic the action of endogenous GLP-1 and have been approved by the FDA and EMA for the treatment of T2DM and obesity (Table 1) [27,28]