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We followed the mice longitudinally for 9 months, tracking their body weight and determining their body composition at the beginning and the end of the experiment (Fig

Given its involvement in metabolic reprogramming and mitochondrial function, targeting PGC-1 could represent a promising strategy for inhibiting metastatic bladder cancer progression and reducing its metastatic potential 30,31

For instance, incorporating a diet rich in antioxidants can protect against oxidative stress, which can degrade collagen and impair muscle function

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doi: 10.1016/j.bbagen.2020.129560