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Amelioration of degenerative phenotypes in park 13 dopaminergic neurons Oxidative stress is one of the major underlying causes of sporadic and familial forms of Parkinsons disease and mainly characterized by an imbalanced GSH/GSSG cycle, enhancing cellular susceptibility to oxidation 37

Together, these antioxidants inhibit tyrosinase, decrease production of eumelanin, and promote the formation of lighter pheomelanin

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Glutathione levels naturally decrease with age

1 2 3 4 "Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology"