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Some other coronaviruses, including those that have a histidine residue at the -3 position in the tail of S, have been found to be efficiently endocytosed if they reach the surface 44,45

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D-Nle-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 exhibited no detectable metabolism over 90 min in an in-vitro metabolism assay using rat liver microsomes (data not shown)

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