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Protective effects and mechanism of polysaccharide from Polygonatum sibiricum on behavioral despair mice

While receptor depletion from the plasma membrane occurs due to the -arresitin binding-induced endocytosis [26], it is reasonable to assume that the receptors are still synthesized and replenished with a rate r s , which leads to the following evolution equation for the receptor density on the cell surface: Dephosphorylation and resensitization of receptor In the longer time scale, it was suggested that typically only after the receptor internalization, protein phosphotases (PPs) are at work in an acidic endosomal compartment to dephosphorylate, resensitize and restore the receptor back to the cell surface [48, 50, 56, 57]

References: Passaretti, S., Iannone, A., Marinelli, M., et al

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The crystals were observed after 1 week in the condition of 0.1 M MESimidazole pH 6.5, 10% w/v PEG 20000, 20% v/v PEG MME 550, 0.02 M sodium l-glutamate, 0.02 M dl-alanine, 0.02 M glycine, 0.02 M dl-lysine HCl and 0.02 M dl-serine

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