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It was found that the combined supplementation of 2 M Lup + 0.75 M Vit A in semen cryopreservation extenders significantly upregulated the transcriptional levels of antioxidant genes such as SOD1 , NRF2 and GPX4 , concurrently, a notable upregulated was also observed with Vit A supplementation alone, and these findings further confirm that the addition of Vit A and Lup enhances antioxidant enzyme levels

doi: 10.1038/ijo.2010.59 63 GaultV

Side effects included nausea (44%), vomiting (24%), diarrhea (30%), constipation (24%), abdominal pain (20%), headache (14%), fatigue (11%), dizziness (8%), abdominal distension (7%), and belching (7%)

Nat Rev Cancer 23 , 372390 (2023)

At this concentration, reaching the standard starting dose of 0.25 mg requires drawing 25 units

And your adrenal glands should never give out, with the exception being Addisons disease, which is an autoimmune disease that results in an adrenal crisis