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The gut microbiota metabolite glycochenodeoxycholate activates TFR-ACSL4-mediated ferroptosis to promote the development of environmental toxin-linked MAFLD

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When a cell over-expresses NNMT, it does two costly things at once: it burns through methyl-donor capacity, and it diverts nicotinamide away from NAD+ regeneration into an inert metabolite (1-methylnicotinamide) that gets excreted

Glucagon-like peptide-1 receptor agonists in diabetic kidney disease: A review of their kidney and heart protection

Balancing blood sugar This cuts cravings for sugary snacks

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