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The first signs of B12 deficiency include persistent fatigue, weakness, lightheadedness, pale skin, tingling or numbness in the hands and feet, difficulty concentrating, and mood changes like irritability or mild depression

On the other hand, two studies have found that circulating IL-17A is elevated in depressed patients (175, 176), and the administration of IL-17A is able to promote depressive-like behaviors (177)

Advanced glycation end products (AGEs) are the outcomes of non-enzymatic glycosylation of either endogenous or exogenous proteins 102

Ein Interview von Matthias Fiedler aus DER SPIEGEL 27/2025

The solution should flow freely when the pen is gently tilted

It involves inflammation of a thick band of tissue known as plantar fascia that runs along the bottom of the feet