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Macrophage studies demonstrate that GHK-Cu administration shifts these cells from a pro-inflammatory M1 phenotype to a tissue-repairing M2 phenotype, increasing their production of growth factors including vascular endothelial growth factor (VEGF) and platelet-derived growth factor (PDGF) by 40-60%

Subgroup analyses were conducted to examine the effects of GLP-1RAs compared to metformin or placebo

doi: 10.5455/jabet.2025.17 69

This review was also limited in that it only included articles available in English and did not access articles behind paywalls, which may have possibly introduced selection or publication bias to the methodology

Radetic M, Kamal A, Rouphael C, Kou L, Lyu R, Cline M (2021) Severe gastroparesis is associated with an increased incidence of slow-transit constipation as measured by wireless motility capsule

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