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In Phase I, the liver breaks down fat-soluble toxins into smaller, often more reactive intermediate molecules

The second enzyme is glutathione reductase (GR)

Hyperglucotoxicity and lipotoxicity increase the expression of islet THADA

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This is why I recommend working with a functional health practitioner who can help you support detoxification in the body so you can turn your MTHFR genes off and heal