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Research has explored its interactions with sleep architecture, neuroendocrine pathways, and stress-response mechanisms, with particular interest in its potential influence on growth hormone secretion and neuroprotective processes during sleep states

Thus, future research should consider the impact of interacting intrinsic genetic as well as extrinsic dietary factors involved in the regulation of IIS

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Therefore, the metabolic pathways of glutamine, tryptophan, and leucine converge on key regulatory nodes such as mTOR, AhR, and epigenetic modifiers, creating a network that dynamically controls Th17/Treg equilibrium