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PMID: 39325560 Sikiric P et al
Hereditary brachydactyly associated with hypertension
Under normal physiological conditions, activation of the Keap1-NRF2 signaling pathway promotes the activation of System Xc - and the expression of GPX4 and accelerates cysteine glutamate transport, thereby clearing accumulated lipid peroxidation and inhibiting ferroptosis (86)
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