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A study by Pyo et al

When oxidative stress is a contributing factor, we offer glutathione therapy to counteract the underlying cause of depression

Glutathione peroxidase 4 (GPX4) is a key suppressor of ferroptosis, which is a glutathione (GSH)-dependent antioxidant enzyme that converts toxic lipid hydroperoxides to nontoxic lipid alcohols 11, 12

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This means AOD 9604 can be used for extended periods without diminishing returns from antibody-mediated inactivation