Indeed, trial NCT05636592 is an active (not currently recruiting) prospective observational study designed the evaluate the safety and efficacy of immune checkpoint inhibitors in combination with statins in advanced non-small cell lung cancer patients
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Data availability The atomic coordinates and electron microscopy maps have been deposited in the Protein Data Bank (PDB) and Electron Microscopy Data Bank (EMDB) under accession codes: 9BP3/EMD-44760 [ (Cagri-AMY 1 R-DNG s complex), 9BLW/EMD-44678 [ (CagriBB-AMY 1 R-DNG s complex), 9BQ3/EMD-44796 [ (Cagri-AMY 2 R-DNG s complex), 9BTW]/EMD-44898 [ (Cagri-AMY 3 R-DNG s complex), 9BUB/EMD-44904 [ (Cagri-CTR-DNG s complex 1, bypass conformation), 9BUD/EMD-44906 [ (Cagri-CTR-DNG s complex 1, CT-like conformation), 9BUC/EMD-44905 [ (Cagri-CTR-DNG s complex 2, bypass conformation), 9BUE/EMD-44907 [ (Cagri-CTR-DNG s complex 2, CT-like conformation), 9BLC/EMD-44653 [ (CagriBB-CTR-DNG s complex 1, CT-like conformation), 9BLB/EMD-44652 [ (CagriBB-CTR-DNG s complex 1, bypass conformation)
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In osteosarcoma, CUR can induce ferroptosis, therebly leading to tumor suppression
Anticonvulsants (phenobarbital, phenytoin, carbamazepine) may decrease serum carnitine in children
