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Longitudinal registries and post-marketing surveillance studies are essential for assessing long-term eye safety, particularly in older populations with multiple health issues

Mounjaro is not indicated for patients with type 1 diabetes or diabetic ketoacidosis

The following schedule is commonly used: In the SURMOUNT-1 study, approximate mean weight change at 72 weeks was 15 per cent for 5mg weekly doses, 19.5 per cent for 10mg weekly dose, and 20.9 per cent for 15mg weekly dose vs ?3.1 per cent with placebo (lifestyle background)

Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus

J Hum Genet 55:565570

The most common side effects are mild nausea, constipation, and diarrhea, especially during the first few weeks