retatrutide and addiction Hot weight loss drugs tested as treatments | Science Q&A: Can weight loss drugs

Consult your prescriber before combining, especially if you also take metformin or other diabetes medications

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In clinical trials, people taking 25 mg of oral semaglutide lost an estimated average of 13.6% of their starting body weight after 64 weeks, compared with 2.2% among those taking a placebo

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The study included 338 participants who were randomized to receive varying doses of retatrutide (1 mg, 4 mg, 8 mg, or 12 mg) or a placebo, administered once weekly for 48 weeks