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Diverse functions of mitochondrial AAA+ proteins: protein activation, disaggregation, and degradation

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xanthohumol (XN), a ligand of PHB2, inhibits autophagic degradation of mitochondria through association with PHB2 binding and inhibiting the binding of PHB2 to LC3, which in turn inhibits mitophagy (Fig

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Additionally, gene ontology analysis identified that Gclc -sufficient MZB transcriptomes showed upregulation of genes that are related to ROS metabolic processes when compared to Gclc -sufficient FoB (Fig

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