10.14735/amko20182S46 105 MasG.HillerS
Since glutathione is rapidly oxidized, much of the glutathione in a supplement would not be absorbed by the gastrointestinal tract, and thus would not to be especially effective for substantially raising tissue glutathione concentration
Glutamine supports immune functions too: for example, T-cell activation requires Alanine-Serine-Cysteine Transporter 2-mediated glutamine uptake to engage mTORC1 and drive proliferation, and glutamine deprivation blocks T-cell proliferation and cytokine production, so complete glutamine elimination should rather be avoided 357
That gap matters
Therefore, whilst palpitations can occur during Wegovy treatment, establishing causality requires careful clinical assessment and consideration of alternative explanations
Clinical data from the PIONEER trials demonstrate significant HbA1c reductions with semaglutide 7mg and 14mg, along with meaningful body weight reduction a dual benefit highly relevant for overweight T2DM patients
