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Marso SP, Daniels GH, Brown-Frandsen K, Kristensen P, et al

This initial dose is generally sub-therapeutic for glycaemic control

This treatment is particularly beneficial for those experiencing dehydration, nutrient deficiencies, or stress-related fatigue

Cardiometabolic disease is used as an umbrella term for all the above cases, and severity of cardiometabolic disease refers, in this manuscript, to the progression from single risk factors such as obesity to overt T2D and cardiac phenotype (ischemic heart disease and heart failure)

This helps offset the list price but does not always translate into lower costs for patients, especially those in high-deductible plans

Supporting this model, transcriptomic analysis of 3xTg-AD mice at different disease stages (2, 10, and 20 months) revealed age-related increases in DAM-associated genes such as Trem2, Tyrobp, Clec7a , and Cd68 , particularly in aged AD mice compared to young AD mice and aged-wild-type controls (Lambracht-Washington et al., 2023)