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Olive phenolics may inhibit ATP synthase through interactions within the ATP synthase polyphenol binding pocket, and residues such as Arg283 have been described as important for this interaction, potentially contributing to reduced ATP generation [111]
Denaturation and reduction steps were optimized to facilitate enzymatic digestion without compromising the lipidated moiety. Enzymatic Digestion A dual-enzyme approach employing Glu-C and chymotrypsin was utilized to generate overlapping peptide fragments, ensuring full sequence coverage
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Selenium is a cofactor for enzymes that synthesize glutathione and detoxify acetaminophen
Polyamines are involved in cell division and proliferation, regulation of gene expression for cell survival, facilitation of DNA and protein synthesis, apoptosis and oxidative stress control, angiogenesis, and cell-to-cell communication (Lenis et al., 2017)
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