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Biomed Res Int 2013:725410 Riesenbeck LM, Bierer S, Hoffmeister I et al (2011) Hypothyroidism correlates with a better prognosis in metastatic renal cancer patients treated with sorafenib or sunitinib

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Set a schedule: Administer your dose on the same day each week to maintain consistent levels in your body

Signs of developing tolerance that community sources describe (typically weeks 4-6): appetite suppression weakening, the energy boost diminishing, return of cravings