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[18] These have established safety profiles and NICE-aligned prescribing pathways

Absorption of other medications can be impacted due to intestinal bypass

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00:11:49 Vickie Danaher But theres no evidence that combos work better to improve weight loss or glycemic control, and it likely increases the risk of side effects, especially nausea, vomiting, and GI intolerance

It explains that protein stimulates native GLP-1 secretion from intestinal L-cells while soluble fiber slows gastric emptying and increases incretin release, mimicking part of what GLP-1 medications do pharmacologically