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3 Newer medication classes, such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium-glucose co-transporter 2 (SGLT-2) inhibitors, target some of the more recently identified defects described in the ominous octet. Agents from these medication classes are increasingly recommended in clinical practice guidelines and recommendations

In the first hour of darkness, no drinking water was provided, and one hour later, ethanol was provided for 4 h continuously

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PMID: 217 UlukanJimenezMKarbachSJeschkeAGraaOKellerJet al

Kidney outcomes in cardiovascular trials: Analyses from SUSTAIN-6, LEADER, and other trials consistently show reductions in kidney-related outcomes with GLP-1 treatment