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3E, Supplementary Fig

Seeing a model that naturally develops diabetes and then progresses to kidney disease in a human-like manner feels both scientifically convincing and strategically important

It is a calculation based on your serum creatinine level, age, sex, and sometimes race

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The assay was performed in a plate 96 wells Sterilin (Fisher Scientific, UK) where 10 L of homogenate was transferred to each well containing 180 L of 0.1 M buffer sodium phosphate pH 8.0, 1 mM EDTA, 10 L of 10 mM 5,5-dithiobis (2-nitrobenzoic acid) (DTNB)

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