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Furthermore, both k p2 and k O2 register as the two most sensitive parameters with respect to the main effects, with k p4 also sensitive

Wolter JM, Mao H, Fragola G, Simon JM, Krantz JL, Bazick HO, et al

A recent regulatory example, accepted by the US EPA, of a non-animal risk assessment for the fungicide chlorothalonil in an occupational scenario combined in vitro PoDs from MucilAir readouts (i.e., TEER, lactate dehydrogenase leakage and resazurin metabolism analyses) with dosimetry information obtained from a computational fluid-particle dynamics (CFPD) model (Corley et al., 2021

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Melatonin has some protective effects by increasing the integrity of the intestinal mucosal barrier, leading to regulation of the immune response [199]