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This can cause a strain on your liver, kidneys, and other organs used in the removal of waste products, using them more than they need to

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Nouri A, Ghatreh-Samani K, Amini-Khoei H, Mohammadi A, Heidarian E, Najafi M (2022) Ferulic acid prevents cyclosporine-induced nephrotoxicity in rats through exerting anti-oxidant and anti-inflammatory effects via activation of Nrf2/HO-1 signaling and suppression of NF-kappaB/TNF-alpha axis

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barbarum berry formulations in a double-blinded, controlled human intervention trial