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Now its unrealistic to expect that weight-loss exercise programs will be effective long-term when you consider how extreme fibromyalgia-related fatigue can be

doi: 10.1016/j.autrev.2020.102614 150 JiangHLingZZhangYMaoHMaZYinYet al

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Tier 3 patients often experience significant improvements in energy levels and brain fog within 2-4 weeks, with substantial weight loss and metabolic improvements within 8-12 weeks, and continued progress over 6-12 months

Both drugs, through independent studies, showed the same pattern: essentially no transfer into breast milk