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The FDA Adverse Event Reporting System (FAERS) contains reports of musculoskeletal complaints associated with GLP-1 use, but such reports do not prove causation and may reflect coincidental associations or other contributing factors

DPP-4 inhibition with alogliptin on top of angiotensin II type 1 receptor blockade ameliorates albuminuria via up-regulation of SDF-1a in type 2 diabetic patients with incipient nephropathy

Proc Natl Acad Sci U S A 2006;103:462833

As a result, fatigue is reduced and overall energy levels are improved, facilitating better daily performance