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[397] found a significantly increased accumulation of dysfunctional mitochondria in the fibroblasts isolated from SLOS patients under steady-state conditions compared to control cells

Allergic: anaphylaxis, urticaria, shortness of breath, wheezing, angioedema CNS: headache, dizziness, agitation, anxiety Dermatologic: rash, erythema, pruritus Ophthalmic: diplopia 7

The WHI estrogen-alone substudy reported no overall effect on CHD events in women receiving estrogen-alone compared to placebo 2[see Clinical Studies (14.5)]

The strengths of the current investigation include its real-world clinical setting with well-characterized medical evaluations and rigorous omics analyses validated by an established feature selection algorithm [89]

Tirzepatide is a synthetic dual-agonist peptide compound produced for research applications