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In the IMPACT trial, pemvidutide achieved mean weight losses of 4.8% and 5.8% with 1.2 and 1.8 mg doses respectively at 24 weeks, compared to 0.5% with placebo, with weight loss curves showing no evidence of plateauing, suggesting continued benefit with longer treatment [49-51]

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The current landscape for diabetes treatment: preventing diabetes-associated CV risk

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Cell Mol

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Medical Realities vs

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Starting with a lower dose and gradually increasing can help minimize discomfort

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Because of this, certain foods can contribute more to the GI side effects, like spicy and high-fat foods

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