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Clinically, GLP-1RAs could lead to an improvement in cognitive function, which is often found to be impaired across several conditions such as psychosis 240 and mood disorders 241 , eventually leading to an overall benefit as observed in some of the included studies (Tables 4 and 5)

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Lancet Diabetes Endocrinol 2022;10:77485.ArticlePubMed 57

The issue is that safety data exists for FDA-approved dosing ranges , not for long-term use at doses below those studied

doi: 10.1016/j.jconrel.2017.03.041

Molecular mechanisms of appetite regulation