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(If you want to follow the author, Professor It makes the point that the benefits of GLP-1s are not just related to weight loss but also that a potentially unifying mechanism of action for GLP-1R agonism is the reduction of inflammation . This led me to another paper, published in Cell Metabolism , where they showed that the action of GLP-1 on the brain causes a decrease in inflammation in the body

[11c]-PK11195 PET: Quantification of Neuroinflammation and a Monitor of Anti-Inflammatory Treatment in Parkinsons Disease

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JAMA 330 , 170181 (2023)

While the extent of liver scarring reduction wasnt explicitly disclosed, Eli Lilly highlighted the drugs clinically meaningful impact across various dosage strengths