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4 Impaired excretion is most often due to abnormalities in the kidney urate transporter (called URAT1) or organic ion transporter (OAT), both of which control the movement of uric acid out of proximal kidney tubules and into urine

Wilkinson K, Koscien CP, Monteyne AJ, Wall BT, Stephens FB

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Inflammation as a therapeutic target for diabetic neuropathies

In terms of treatment, MGBA-targeted interventionsincluding probiotics, prebiotics, and fecal microbiota transplantationhave shown promise in improving the gut environment, modulating immune-inflammatory responses, and alleviating behavioral symptoms in ASD