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Shaking the vial, using the wrong diluent, or injecting the water too forcefully can shear the amino acid bonds

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Dosing Schedules from Published Research Phase 2 Trial Dose Groups The Phase 2 clinical trial published in NEJM employed the following dose groups, all administered via subcutaneous injection once weekly: Scroll sideways to view the full table on mobile

Oral vs Intravenous Indeed, after several searches in scientific literature, only a single case report was found describing a possible link between oral methylene blue and serotonin syndrome 27

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